Understanding the fuse locations in your 2006 Ford E-250, especially for systems related to the 4.6L engine and OBD2 port, is crucial for quick troubleshooting of electrical issues. Fuses protect your vehicle’s electrical circuits from overloads, and knowing their locations can save you time and money on repairs. This guide will walk you through the fuse box locations in your 2006 Ford E-250, providing diagrams and details to help you find the right fuse every time.
The 2006 Ford E-250 actually utilizes four distinct fuse boxes, each serving different systems within your van. Knowing where each is located is the first step to resolving electrical problems. Let’s explore each of these locations to ensure you can efficiently find the fuse you need.
First, let’s look at the Passenger Compartment Fuse Panel. This fuse box is typically the first place to check for issues related to interior functions.
Next, we have the Power Distribution Box, often found in the engine compartment. This box manages higher amperage fuses and relays for major vehicle systems.
The Instrument Panel Relay Module is another important location, managing relays for various instrument panel functions.
Lastly, the Engine Compartment Relay Module is critical for engine management and related systems. This is a key area when diagnosing issues related to your 4.6L engine and potentially the OBD2 system.
Below are detailed tables outlining the fuses and their functions for the Passenger Compartment Fuse Panel and the Power Distribution Box. While the OBD2 port itself may not have a dedicated fuse labeled “OBD2,” it’s often linked to fuses that power the Powertrain Control Module (PCM) or diagnostic systems. In the Passenger Compartment Fuse Panel, Fuse #26 (20A) is designated for “Cigar lighter, Diagnostics,” which likely powers the OBD2 port. Additionally, Fuse #8 (30A) relates to “Powertrain Control Module (PCM) diode, PCM power relay,” which is critical for engine operation and diagnostics.
Passenger Compartment Fuse Panel Fuses:
Type | No. | Description |
---|---|---|
Fuse MINI 5A | 1 | 4-Wheel Anti-lock Brake System (4WABS) module |
Fuse MINI 10A | 2 | Remote Keyless Entry (RKE), O/D cancel, IVD module |
Fuse MINI 15A | 3 | Trip computer, Radio, Overhead console |
Fuse MINI 15A | 4 | Courtesy lamps |
Fuse MINI 30A | 5 | Power lock switches, Power locks without RKE |
Fuse MINI 10A | 6 | Brake-shift interlock, Daytime Running Lamps (DRL) module |
Fuse MINI 10A | 7 | Multi-function switch, Turn signals |
Fuse MINI 30A | 8 | Radio capacitor(s), Ignition coil, Powertrain Control Module (PCM) diode, PCM power relay |
Fuse MINI 5A | 9 | Wiper control module |
Fuse MINI 20A | 10 | Main light switch, Park lamps, License lamp (external lamps), Multi-function switch (flash-to-pass) |
Fuse MINI 15A | 11 | Multi-function switch (hazards), Brake lamp switch, Brake lamps |
Fuse MINI 15A | 12 | Back-up lamps, Auxiliary battery relay [gasoline engine only] |
Fuse MINI 15A | 13 | Blend door actuator, Function selector switch |
Fuse MINI 5A | 14 | Instrument cluster |
Fuse MINI 5A | 15 | Trailer battery charge relay, Cluster |
Fuse MINI 30A | 16 | Power seats |
Fuse MINI 5A | 17 | Power mirrors |
Fuse MINI 10A | 20 | Restraints |
Fuse MINI 15A | 22 | Memory power radio, Battery saver relay, Instrument cluster, Courtesy lamp relay, Accessory delay relay |
Fuse MINI 20A | 23 | Power locks w/RKE |
Fuse MINI 10A | 25 | Left headlamp (low beam) |
Fuse MINI 20A | 26 | Cigar lighter, Diagnostics |
Fuse MINI 5A | 27 | Radio |
Fuse MINI 15A | 30 | Headlamps (high beam indicator) |
Fuse MINI 10A | 31 | Right headlamp (low beam) |
Fuse MINI 20A | 32 | Power point #1 (instrument panel) |
Fuse MINI 10A | 33 | Start relay |
Fuse MINI 30A | 34 | IP Body builder connector #3 |
Fuse MINI 5A | 36 | Instrument illumination |
Fuse MINI 5A | 37 | Airbag deactivation switch |
Fuse MINI 10A | 39 | Trailer tow electric brake, Center High-Mounted Stop Lamp (CHMSL), Brake lamps |
Fuse MINI 20A | 40 | Power point #2 (2nd row seating position – driver side) |
Fuse MINI 30A | 41 | Modified vehicle |
Circuit breaker ATO | 42 | Power windows |
Circuit breaker ATO | 44 | Wiper/washer |




Power Distribution Box Fuses:
Type | No. | Description |
---|---|---|
Diode ATO | 1 | Powertrain Control Module (PCM) diode |
Diode ATO | 2 | Auxiliary battery diode |
Fuse MINI 15A | 3 | Daytime Running Lamps (DRL) module, A/C clutch |
Fuse MINI 5A | 4 | Heated PCV [4.6L and 6.8L gasoline engines] |
Fuse MINI 15A | 5 | Horn relay |
Fuse MINI 2A | 6 | Brake pressure switch |
Fuse MAXI 60A | 7 | Ignition switch, Accessory delay |
Fuse MAXI 40A | 8 | Trailer battery charge relay |
Fuse MAXI 50A | 9 | Modified vehicle power |
Fuse MAXI 30A | 10 | Electric brake controller |
Fuse MAXI 60A | 11 | [4-Wheel Anti-lock Brake System (4WABS)] / [AdvanceTrac with RSC] |
Fuse MAXI 60A | 12 | I/P fuses 29, 34, 35, 40 and 41 |
Fuse MAXI 20A | 13 | Fuel pump relay |
Fuse MAXI 50A | 14 | Auxiliary blower relay |
Fuse MAXI 30A | 15 | Main light switch |
Fuse MAXI 20A | 16 | Injectors [gasoline engines] |
Fuse MAXI 50A | 17 | Blower motor relay (blower motor) |
Fuse MAXI 60A | 18 | Engine compartment fuses 3, 5 and 26, Instrument panel fuses 26 and 32, Start relay |
Fuse MAXI 50A | 19 | IDM relay [diesel engine only] / AdvanceTrac with RSC [gasoline engines only ] |
Fuse MAXI 60A | 20 | Auxiliary battery relay [gasoline engine only], PDB fuses 8 and 24 |
Fuse MAXI 30A | 21 | PCM power relay, PDB fuse 27 |
Fuse MAXI 60A | 22 | I/P fuses 4, 5, 10, 11, 16, 17, 22 and 23, Circuit breaker 44 |
Fuse MINI 10A | 23 | Alternator field [diesel engine only] |
Fuse MINI 20A | 23 | CMS, HEGOS, MAF, EGR, A/C clutch relay [gasoline engine only] |
Fuse MINI 20A | 24 | Trailer tow running lamps and back-up lamp relays |
Fuse MINI 20A | 26 | Trailer tow turn signals |
Fuse MINI 10A | 27 | PCM |
Relay | A | Fuel pump relay |
Relay | B | Horn relay |
Relay | C | Trailer back-up lamps relay |
Relay | D | Trailer running lamps relay |
Relay | E | Trailer battery charge relay |
Relay | F | IDM relay [diesel only], IVD [gasoline only] |
Relay | G | PCM relay |
Relay | H | Blower motor relay |
Relay | J | Accessory delay relay |
Relay | K | Start relay |
When dealing with OBD2 port issues on your 2006 Ford E-250 4.6L, checking Fuse #26 in the Passenger Compartment Fuse Panel is a good starting point. For engine-related problems, especially those that might affect OBD2 diagnostics, fuses related to the PCM in both the Passenger Compartment and Power Distribution Box should be examined. Always refer to your vehicle’s owner’s manual for the most accurate fuse information and diagrams, as there can be variations. This guide serves as a helpful reference to get you started in locating the fuses in your 2006 Ford E-250.